The Aviation Artwork Collection contains original artworks on paper and reprints of artwork with themes related to air travel, aircraft, air battles, and other aviation topics. This is an artificial collection that brings together materials from a variety of sources. Numerous media and techniques are present, including acrylic, watercolor, gouache, etching, and graphite, but the collection is primarily made up of lithographic and poster reprints. The collection is organized alphabetically by artist with more than 140 artists represented.

Each series within the collection consists of works by an individual artist, with works by unidentified artists grouped together. Some notable artists include George Akimoto, John Amendola, Chesley Bonestell, Robert Carlin, Donald Croly, James Dietz, Uwe Feist, Richard Hunt, Mike Machat, Robert Parks, Stan Stokes, and Fred Takasumi. Some limited-edition series of artworks are also present, such as the Gathering of Eagles collection by Jay Ashurst from the 1980s and 1990s which commemorate famous aviators. Prints in traditional Kwa-Gulth style by indigenous artits Jim Johnny and Richard Hunt are also present.

Common subjects in the collection include commercial, military, and civil aircraft with Boeing aircraft especially well represented; military air skirmishes; historic flights; portraits of pilots; and some landscape scenes.